Washington D.C. [US], Feb. 26 (ANI): US researchers have warned, Donepezil, a medication that is approved to treat people with Alzheimer’s disease, should not be prescribed for people with mild cognitive impairment, without a genetic test.

Researchers from the University Of California discovered that for people who carry a specific genetic variation, the K-variant of butyrylcholinesterase, or BChE-K donezpezil, could accelerate cognitive decline.

The study has been published in Journal of Alzheimer’s Disease.

Mild cognitive impairment is a transitional state between normal age-related changes in cognition and dementia.